What’s New, and What Works, in the 2025 Metabolism-Boosting Supplements List
Each year, the health and wellness industry introduces new supplements that promise to boost your metabolism and help you reach your fitness goals. As we embark into 2025, the demand for evidence-based, safe and efficient metabolism-friendly support solutions has never been louder. Here is a primer on the most popular supplements this year, along with what the latest research shows does — or doesn’t — work.
1. Green Tea Extract (EGCG)
Green tea extract is still a mainstay in metabolism-revving weight-loss supplements. Its active ingredient, EGCG (epigallocatechin gallate), is believed to help increase calorie burning and fat oxidation. In 2025, breakthrough formulations, offering optimal bioavailability ensure this traditional supplement is even more of a success.
2. Berberine
Berberine, a substance extracted from plants, is becoming a trending ingredient as it promotes healthy blood sugar levels and metabolism. Newer research indicates it might aid in increasing insulin sensitivity and body fat loss, which would make it a top choice if you're trying to crank up your metabolism naturally.
3. Capsaicin & Capsiate
Found in chili peppers, capsaicin and its less fiery relative capsiate have been shown to boost thermogenesis (or the creation of heat within the body) – and that means burning more calories. New 2025 versions provide sustained-release caplets for hours of relief from heartburn with acid reflux and more complete coverage day or night.
4. L-Carnitine
L-Carnitine transports fatty acids into the cell for energy production. It’s not a magic bullet, but research suggests it can help both exercise performance and fat metabolism, as long as it’s combined with regular physical activity, of course.
5. Fucoxanthin
This marine carotenoid, which is present in brown seaweed, has made it onto the radar in 2025 for its ability to induce an elevation in resting metabolic rate and facilitate fat reduction and weight loss in the abdominal region. Your best bet is to buy high-purity fucoxanthin supplements.
6. Caffeine + Theacrine Blends
Caffeine is a tried-and-true metabolism lifter, but in 2025, it’s frequently joined by theacrine, a substance that acts like caffeine, yielding energy, but without the jitters or the crash. These pre-workout and daily energy supplements are in high demand.
7. Probiotics (Specific Strains)
New studies focus on metabolism and gut health. Some probiotic types, for example, Lactobacillus gasseri and Bifidobacterium breve, are now added in metabolism-targeting supplements to benefit the gut microbiome associated with healthy metabolism.
8. Ashwagandha
Traditionally favoured for its stress-reducing impacts, ashwagandha is gaining a reputation for its ability to assist thyroid function and metabolic rate in those with sub-clinical hypothyroid or a slow metabolism due to stress or hormonal imbalance.
9. Alpha-Lipoic Acid (ALA)
ALA is an antioxidant that assists with the conversion of glucose into energy and may improve insulin sensitivity. In 2025, it’s frequently incorporated into metabolism-boosting combinations for its energizing and blood sugar support effects.
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